Ok, i guess everybody noticed that importing adserver lists from websites like yoyo brings down most input managers for Safari. Even the userContent.css from floppymoose is slowing down the tab creation process in Safari.
After testing a lot with diffrent solutions i made up this final one:
Get the host list for macs from yoyo and edit your /etc/hosts.
Get Saft and delete all the URL match Patterns (and uncheck "Block Ad/Banners"). So you have the nice Fullscreen function for your Safari and more advanced controls about many other things in the browser. You can bind the Fullscreen shortcut to cocoasuite what i use for my global mous egestures in Mac OS X.
Next get SafariBlock v1.14 and delete all preset Filters. The special in SafariBlock is that you have a right-click on images, frames and flash movies to block em and set up filter rules for em. Works pretty well and the performance is still very good, as it would be without all these tools.